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how do i remove a trojan requester and a vbs.generic.278?

i have a trojan.requester and a vbs.generic.278 i have pc-cillin internet security 2005 on my computer but it does not pick them up! and it is up to date on viru defentions but when i do a stop sign online scan it comes up with these two virus help someone please thanxs.
james, December 2004
hey. ow did u manage 2 get tht? bcz me and my firends are all getting it off msn - it automatically sends itself. ive managed to remove the trojan with BT Yahoo Anti-Spy but that doesnt get rid of the infected files. im now using another anti-virus software that i found off google called Stop-Sign.
it seems to be working.

Jess, November 2005
p.s i have turned off my system restore an restarted my computer b4 i do both scans please please help cheers james

james, December 2004
link Click here to see other fixes for Trend Micro.